Alignment-Free Ultra-High-Throughput Comparison of Druggable Protein-Ligand Binding Sites.
Nathanael WeillDidier RognanPublished in: J. Chem. Inf. Model. (2010)
Keyphrases
- protein protein
- high throughput
- binding sites
- virtual screening
- protein protein interactions
- sequence alignment
- microarray
- genome wide
- gene expression
- dna binding
- proteomic data
- computational methods
- systems biology
- biological data
- transcription factors
- interaction networks
- mass spectrometry
- sequence data
- gene expression levels
- genomic data
- statistical significance
- data acquisition
- protein interaction
- transcriptional regulation
- predicting protein
- biomedical literature
- biological processes
- protein sequences
- high speed
- mass spectrometry data
- motif discovery
- dna sequences
- microarray data
- pairwise
- regulatory networks
- protein complexes
- gene expression data
- biological sequences
- drug discovery
- data mining
- transcription factor binding sites
- molecular biology