Sequence-only evolutionary and predicted structural features for the prediction of stability changes in protein mutants.
Lukas FolkmanBela StanticAbdul SattarPublished in: BMC Bioinform. (2013)
Keyphrases
- structural features
- secondary structure
- psi blast
- multiple sequence alignments
- rna molecules
- experimentally determined
- protein structure prediction
- protein sequences
- multiple sequence alignment
- amino acids
- protein structure
- chemical compounds
- contact map
- sequence analysis
- sequence alignment
- amino acid sequences
- computational methods
- structural information
- rna secondary structures
- protein folding
- phylogenetic trees
- rna sequences
- semantic features
- sequence databases
- protein interaction
- genome sequences
- biological sequences
- clustering algorithm
- protein protein interactions
- computational biology
- training data