Incorporating family disease history and controlling case-control imbalance for population-based genetic association studies.
Yongwen ZhuangBrooke N. WolfordKisung NamWenjian BiWei ZhouCristen J. WillerBhramar MukherjeeSeunggeun LeePublished in: Bioinform. (2022)
Keyphrases
- association studies
- haplotype inference
- genome wide
- linkage disequilibrium
- single nucleotide polymorphisms
- high throughput
- complex diseases
- entropy minimization
- genetic algorithm
- human genome
- simulated annealing
- special case
- answer set programming
- branch and bound algorithm
- particle swarm optimization
- combinatorial optimization
- model selection
- upper bound
- neural network