A multi-Poisson dynamic mixture model to cluster developmental patterns of gene expression by RNA-seq.
Meixia YeZhong WangYaqun WangRongling WuPublished in: Briefings Bioinform. (2015)
Keyphrases
- gene expression
- mixture model
- rna seq
- gene expression patterns
- microarray
- em algorithm
- generative model
- gene expression data
- microarray data
- high throughput
- expectation maximization
- clustering algorithm
- gene regulation
- biological processes
- probabilistic model
- unsupervised learning
- maximum likelihood
- language model
- alternative splicing
- model selection
- biological networks
- gene expression profiles
- binding sites
- biological data
- high dimensionality
- genomic data
- microarray datasets
- gene selection
- feature space