Development of an experiment-split method for benchmarking the generalization of a PTM site predictor: Lysine methylome as an example.
Guoyang ZouYang ZouChenglong MaJiaojiao ZhaoLei LiPublished in: PLoS Comput. Biol. (2021)
Keyphrases
- main contribution
- machine learning
- similarity measure
- optimization method
- fully automatic
- high precision
- detection method
- significant improvement
- high accuracy
- computational cost
- segmentation method
- synthetic data
- experimental evaluation
- pairwise
- preprocessing
- website
- information retrieval
- neural network
- computationally efficient
- evolutionary algorithm
- clustering method
- error rate
- objective function
- bayesian networks
- modular neural network