Motif Discovery Through Predictive Modeling of Gene Regulation.
Manuel MiddendorfAnshul KundajeMihir ShahYoav FreundChris WigginsChristina S. LesliePublished in: RECOMB (2005)
Keyphrases
- gene regulation
- motif discovery
- transcription factors
- binding sites
- regulatory networks
- gene expression
- dna sequences
- biological networks
- microarray
- systems biology
- data mining methods
- component analysis
- computational biology
- genome wide
- gene expression data
- biological sequences
- gene regulatory networks
- biological systems
- high throughput
- pattern discovery
- multiobjective optimization
- sequence data
- data mining tasks
- highly correlated
- data mining
- molecular biology
- biomedical literature
- decision trees
- machine learning
- co occurrence
- text mining
- preprocessing
- statistical significance
- data analysis
- database
- dimensionality reduction
- information retrieval
- data mining algorithms