Optimization algorithms for functional deimmunization of therapeutic proteins.
Andrew S. ParkerWei ZhengKarl E. GriswoldChris Bailey-KelloggPublished in: BMC Bioinform. (2010)
Keyphrases
- optimization problems
- discrete optimization
- data structure
- combinatorial optimization
- stochastic gradient
- protein sequences
- optimization procedure
- machine learning
- learning algorithm
- evolutionary algorithm
- significant improvement
- worst case
- simulated annealing
- computationally efficient
- benchmark datasets
- convex optimization