Protein target similarity is positive predictor of in vitro antipathogenic activity: a drug repurposing strategy for Plasmodium falciparum.
Reagan M. MogireSilviane A. MirukaDennis W. JumaCase W. McNamaraBen AndagaluJeremy N. BurrowsElodie ChenuJames DuffyBernhards OgutuHoseah M. AkalaPublished in: J. Cheminformatics (2024)
Keyphrases
- drug discovery
- similarity measure
- chemical compounds
- drug design
- protein structure
- neural network
- protein sequences
- distance function
- positive and negative
- protein structure alignment
- virtual screening
- physico chemical
- protein structure prediction
- target tracking
- protein protein interactions
- mass spectrometry
- sequence similarity
- structural similarities
- magnetic resonance spectroscopy
- amino acids