A Nested 2-Level Cross-Validation Ensemble Learning Pipeline Suggests a Negative Pressure Against Crosstalk snoRNA-mRNA Interactions in Saccharomyces cerevisiae.
Antoine SouléJean-Marc SteyaertJérôme WaldispühlPublished in: J. Comput. Biol. (2020)
Keyphrases
- biological data
- cross validation
- saccharomyces cerevisiae
- ensemble learning
- regulatory networks
- gene regulatory networks
- microarray data
- model selection
- generalization ability
- protein protein interactions
- ensemble methods
- hyperparameters
- support vector
- interaction networks
- training set
- gene expression
- base classifiers
- random forest
- data sets
- unlabeled data
- microarray
- pairwise
- machine learning
- machine learning methods
- binding sites