Bayesian inference for identifying tumour-specific cancer dependencies through integration of ex-vivo drug response assays and drug-protein profiling.
Hanwen XingChristopher YauPublished in: BMC Bioinform. (2024)
Keyphrases
- bayesian inference
- drug discovery
- virtual screening
- chemical compounds
- drug design
- probabilistic model
- physico chemical
- prior information
- hyperparameters
- variational inference
- statistical inference
- bayesian model
- hierarchical bayesian
- cancer diagnosis
- variational bayes
- gibbs sampler
- protein structure prediction
- medical images
- data sets
- cell lines
- state space
- bayesian models
- protein structure
- binding sites