A cautionary note for retrocopy identification: DNA-based duplication of intron-containing genes significantly contributes to the origination of single exon genes.
Yong E. ZhangMaria D. VibranovskiBenjamin H. KrinskyManyuan LongPublished in: Bioinform. (2011)
Keyphrases
- alternative splicing
- dna sequences
- gene expression
- sequence data
- coding regions
- gene expression data
- human genome
- microarray data
- cis regulatory
- microarray gene expression data
- genomic sequences
- genome sequences
- gene prediction
- sequenced genomes
- rna seq
- gene ontology
- candidate genes
- comparative genomics
- protein coding regions
- microarray data analysis
- gene networks
- gene clusters
- data sets
- gene expression profiles
- gene selection
- metabolic pathways
- genomic data
- regulatory networks
- dna binding
- systems biology
- biological networks
- gene regulatory networks
- high throughput
- transcriptional regulatory