Efficiently Predicting Hot Spots in PPIs by Combining Random Forest and Synthetic Minority Over-Sampling Technique.
Xiaolong ZhangXiaoli LinJiafu ZhaoQianqian HuangXin XuPublished in: IEEE ACM Trans. Comput. Biol. Bioinform. (2019)
Keyphrases
- random forest
- hot spots
- protein protein interactions
- computational methods
- decision trees
- high throughput
- feature set
- gene ontology
- ensemble methods
- protein interaction
- biological data
- high precision
- network topology
- class distribution
- network analysis
- ppi networks
- active learning
- knowledge discovery
- social network analysis
- multi label
- end to end
- base classifiers
- structural properties
- multi class
- machine learning
- statistical methods
- data analysis
- training data