A Zoom-Focus algorithm (ZFA) to locate the optimal testing region for rare variant association tests.
Maggie Haitian WangHaoyi WengRui SunJack LeeWilliam Ka Kei WuKa Chun ChongBenny ZeePublished in: Bioinform. (2017)
Keyphrases
- frequent patterns
- dynamic programming
- learning algorithm
- optimal solution
- worst case
- path planning
- expectation maximization
- detection algorithm
- np hard
- cost function
- region of interest
- globally optimal
- preprocessing
- objective function
- convergence rate
- locally optimal
- optimization algorithm
- linear programming
- particle swarm optimization
- neural network
- high accuracy
- computational cost
- k means
- computational complexity
- shortest path
- simulated annealing
- search space
- optimal strategy
- optimal parameters
- optimal path
- optimal segmentation