Resolving single-cell heterogeneity from hundreds of thousands of cells through sequential hybrid clustering and NMF.
Meenakshi VenkatasubramanianKashish ChetalDaniel J. SchnellGowtham AtluriNathan SalomonisPublished in: Bioinform. (2020)
Keyphrases
- nonnegative matrix factorization
- document clustering
- clustering algorithm
- grid cells
- negative matrix factorization
- clustering method
- stem cell
- microscope images
- unsupervised learning
- spectral clustering
- matrix factorisation
- data points
- k means
- microscopy images
- cancer cells
- fluorescence microscopy images
- information theoretic
- cell division
- manufacturing cell
- phase contrast
- data clustering
- cluster analysis
- probabilistic latent semantic analysis
- living cells
- feature selection
- fuzzy clustering
- similarity measure
- hierarchical clustering
- nonnegative matrix
- document collections