Structure-based design of oxygen-linked macrocyclic kinase inhibitors: discovery of SB1518 and SB1578, potent inhibitors of Janus kinase 2 (JAK2) and Fms-like tyrosine kinase-3 (FLT3).
Anders PoulsenAnthony WilliamStéphanie BlanchardAngeline LeeHarish NagarajHaishan WangEeling TeoEvelyn TanKee Chuan GohBrian DymockPublished in: J. Comput. Aided Mol. Des. (2012)