Discovery of Small Molecule Inhibitors of Protein-Protein Interactions Using Combined Ligand and Target Score Normalization.
Fergal P. CaseyEmilie PihanDenis C. ShieldsPublished in: J. Chem. Inf. Model. (2009)
Keyphrases
- protein protein interactions
- protein protein
- high throughput
- drug design
- score normalization
- computational methods
- wet lab
- biological data
- systems biology
- speaker verification
- protein interaction
- protein complexes
- network analysis
- high precision
- drug discovery
- meta search
- protein function
- person authentication
- network topology
- knowledge discovery
- protein interaction networks
- feature selection
- structural properties
- data fusion
- microarray
- rank aggregation