Explicit representation of protein activity states significantly improves causal discovery of protein phosphorylation networks.
Jinling LiuXiaojun MaGregory F. CooperXinghua LuPublished in: BMC Bioinform. (2020)
Keyphrases
- information retrieval
- protein sequences
- amino acids
- protein structure
- causal discovery
- knowledge discovery
- protein interaction networks
- data mining
- mass spectrometry
- protein function
- physicochemical properties
- social networks
- signaling pathways
- protein protein interaction networks
- causal structure
- real world
- experimentally determined
- protein complexes
- causal models
- classification accuracy
- decision making
- machine learning