Improvements in the reconstruction of time-varying gene regulatory networks: dynamic programming and regularization by information sharing among genes.
Marco GrzegorczykDirk HusmeierPublished in: Bioinform. (2011)
Keyphrases
- information sharing
- gene regulatory networks
- dynamic programming
- gene expression data
- reverse engineering
- gene regulatory
- network model
- yeast cell cycle
- microarray gene expression data
- gene networks
- regulatory networks
- gene interactions
- systems biology
- biological data
- bayesian inference
- gene regulation
- genetic regulatory networks
- saccharomyces cerevisiae
- clustering gene expression data
- dynamic bayesian networks
- share information
- biological processes
- interaction networks
- gene expression
- structure learning
- prior information
- microarray data
- microarray
- state space
- biological knowledge
- stereo matching
- data model
- machine learning
- neural network
- high throughput
- gene function
- graphical models
- artificial intelligence