): A Provable and Efficient Ensemble-Based Algorithm to Optimize Stability and Binding Affinity over Large Sequence Spaces.
Adegoke OjewoleJonathan D. JouVance G. FowlerBruce Randall DonaldPublished in: RECOMB (2017)
Keyphrases
- times faster
- single pass
- experimental evaluation
- expectation maximization
- detection algorithm
- dynamic programming
- computationally efficient
- learning algorithm
- input data
- np hard
- long sequences
- high accuracy
- computational complexity
- optimal solution
- theoretical analysis
- optimization algorithm
- high efficiency
- worst case
- simulated annealing
- computational cost
- k means
- preprocessing
- linear programming
- probabilistic model
- cost function
- significant improvement
- segmentation algorithm
- search space
- search algorithm
- objective function
- pruning strategy
- similarity measure