How Good Are State-of-the-Art Docking Tools in Predicting Ligand Binding Modes in Protein-Protein Interfaces?
Dennis M. KrügerGisela JessenHolger GohlkePublished in: J. Chem. Inf. Model. (2012)
Keyphrases
- protein protein
- predicting protein
- protein protein interactions
- hiv protease
- computational methods
- high throughput
- protein sequences
- protein function
- interaction networks
- binding sites
- drug design
- secondary structure
- protein structure
- computational tools
- protein interaction
- functional modules
- protein complexes
- network topology
- computational approaches
- biological knowledge
- protein interaction networks
- high precision
- network analysis
- systems biology
- molecular biology
- computational biology