Free Energy Profile and Kinetics of Coupled Folding and Binding of the Intrinsically Disordered Protein p53 with MDM2.
Rongfeng ZouYang ZhouYong WangGuanglin KuangHans ÅgrenJunchen WuYaoquan TuPublished in: J. Chem. Inf. Model. (2020)
Keyphrases
- free energy
- protein folding
- amino acids
- intrinsically disordered
- amino acid sequences
- protein sequences
- secondary structure
- protein structure
- protein structure prediction
- upper bound
- belief propagation
- fixed point
- disordered regions
- approximate inference
- experimentally determined
- protein function
- competitive learning
- molecular biology
- graphical models
- machine learning
- coarse grained
- sequence alignment
- neural network
- posterior distribution
- lower bound
- hiv protease
- bayesian networks