EDGA: A Population Evolution Direction-Guided Genetic Algorithm for Protein-Ligand Docking.
Boxin GuanChangsheng ZhangJiaxu NingPublished in: J. Comput. Biol. (2016)
Keyphrases
- genetic algorithm
- evolution process
- natural selection
- evolutionary process
- ligand docking
- multi population
- population size
- evolutionary algorithm
- fitness function
- population dynamics
- mutation operator
- multiple sequence alignment
- protein structure
- initial population
- genetic operators
- crossover and mutation
- binary strings
- metaheuristic
- fitness landscape
- evolutionary computation
- subcellular localization
- neural network
- protein structure prediction
- fuzzy logic
- multi objective optimization
- hybrid algorithm
- mass spectrometry
- crossover operator
- multi objective
- differential evolution
- protein sequences
- particle swarm optimization
- tabu search
- protein interaction data
- island model
- genetic algorithm ga
- evolutionary game theory
- artificial neural networks
- protein function
- amino acids
- sequence alignment
- drug discovery