Statistical analysis of GC-biased gene conversion and recombination hotspots in eukaryotic genomes: a phylogenetic hidden Markov model-based approach.
Meijun GaoKevin J. LiuPublished in: BCB (2021)
Keyphrases
- hidden markov models
- gene conversion
- statistical analysis
- phylogenetic analysis
- phylogenetic trees
- horizontal gene transfer
- gene duplication
- multiple models
- speech recognition
- genome sequences
- hidden states
- sequential data
- evolutionary history
- viterbi algorithm
- dna sequences
- molecular biology
- sequenced genomes
- hidden state
- conditional random fields
- gene trees
- markov model
- rare class
- hierarchical hidden markov model
- statistical methods
- human genome
- binding sites
- handwritten word recognition
- bayesian networks
- anomaly detection
- ensemble methods
- dynamic model