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Simulating autosomal genotypes with realistic linkage disequilibrium and a spiked-in genetic effect.
Min Shi
David M. Umbach
Alison S. Wise
Clarice R. Weinberg
Published in:
BMC Bioinform. (2018)
Keyphrases
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linkage disequilibrium
genome wide
association studies
single nucleotide polymorphisms
genome wide association studies
complex diseases
haplotype inference
human genome
high throughput
disease genes
genetic algorithm
computational approaches
variable selection