Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions.
Ian R. VernonJunli LiuMichael GoldsteinJames RoweJen ToppingKeith LindseyPublished in: BMC Syst. Biol. (2018)
Keyphrases
- systems biology
- gene regulatory networks
- high throughput
- biological systems
- biochemical networks
- complex systems
- signaling pathways
- microarray
- data analysis
- data sets
- gene expression data
- cell biology
- interaction networks
- biological data
- dna sequences
- computational models
- high dimensionality
- maximum likelihood
- knowledge discovery
- probabilistic model
- databases