Genotyping and inflated type I error rate in genome-wide association case/control studies.
Joshua N. SampsonHongyu ZhaoPublished in: BMC Bioinform. (2009)
Keyphrases
- error rate
- genome wide
- genome wide association studies
- high throughput
- single nucleotide polymorphisms
- complex diseases
- test set
- human genome
- data acquisition
- misclassification rate
- expected loss
- lower error rates
- gene gene interactions
- association studies
- microarray
- machine learning
- linkage disequilibrium
- biological data
- equal error rate
- computational approaches
- transcription factors