Identification, Synthesis, and Biological Evaluations of Potent Inhibitors Targeting Type I Protein Arginine Methyltransferases.
Xiao LiLun ZhangJing XuChenyu LiuXiaojian ZhangAmr Abbas AbdelmoneimQian ZhangJiaqi KeYingnan ZhangLei WangFan YangCheng LuoJia JinFei YePublished in: J. Chem. Inf. Model. (2022)
Keyphrases
- protein protein interactions
- mass spectrometry
- protein structure prediction
- drug discovery
- protein interaction
- protein protein
- drosophila melanogaster
- protein interaction data
- protein complexes
- biological processes
- protein sequences
- regulatory networks
- biological data
- tandem mass spectrometry
- physicochemical properties
- high throughput
- interaction networks
- type ii
- protein protein interaction networks
- molecular biology
- mass spectrometry data
- drug design
- computational methods
- computational approaches
- protein function
- functional modules
- computational biology
- biological entities
- wet lab
- sequence analysis
- gene expression analysis
- contact map
- amino acids
- protein structure
- protein interaction networks
- cell lines
- physico chemical
- systems biology