Algorithm for optimized mRNA design improves stability and immunogenicity.
He ZhangLiang ZhangAng LinCongcong XuZiyu LiKaibo LiuBoxiang LiuXiaopin MaFanfan ZhaoHuiling JiangChunxiu ChenHaifa ShenHangwen LiDavid H. MathewsYujian ZhangLiang HuangPublished in: Nat. (2023)
Keyphrases
- cost function
- learning algorithm
- case study
- times faster
- computational cost
- improved algorithm
- optimal solution
- optimization algorithm
- dynamic programming
- genetic algorithm
- computationally efficient
- high accuracy
- worst case
- np hard
- significant improvement
- k means
- experimental evaluation
- detection algorithm
- computational complexity
- linear programming
- search space
- matching algorithm
- recognition algorithm
- neural network