Combinatorial RNA Design: Designability and Structure-Approximating Algorithm in Watson-Crick and Nussinov-Jacobson Energy Models.
Jozef HalesAlice HéliouJán ManuchYann PontyLadislav StachoPublished in: Algorithmica (2017)
Keyphrases
- probabilistic model
- optimization algorithm
- k means
- learning algorithm
- computational complexity
- graph structure
- cost function
- np hard
- detection algorithm
- significant improvement
- dynamic programming
- experimental evaluation
- preprocessing
- search space
- bayesian framework
- objective function
- design process
- rna secondary structure prediction
- parameter estimation
- segmentation algorithm
- model selection
- computational cost
- optimal solution
- image sequences