Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian prior.
Yohan KimJohn SidneyClemencia PinillaAlessandro SetteBjörn PetersPublished in: BMC Bioinform. (2009)
Keyphrases
- amino acids
- similarity matrix
- spectral clustering
- protein sequences
- immune response
- pairwise
- similarity measure
- co occurrence
- secondary structure
- dimension reduction
- protein structure
- mhc class ii
- sequence alignment
- binding peptides
- clustering method
- protein structure prediction
- amino acid sequences
- latent semantic indexing
- protein function
- amino acid residues
- computational biology
- image segmentation
- physico chemical
- clustering algorithm