Heuristic refinement method for the derivation of protein solution structures: validation on cytochrome b562.
James F. BrinkleyRuss B. AltmanBruce S. DuncanBruce G. BuchananOleg JardetzkyPublished in: J. Chem. Inf. Comput. Sci. (1988)
Keyphrases
- optimization method
- high precision
- high accuracy
- mathematical model
- preprocessing
- pairwise
- significant improvement
- cost function
- computational cost
- detection method
- initial solution
- optimization algorithm
- closed form
- multiple sequence alignments
- genetic algorithm
- search procedure
- dynamic programming
- evolutionary algorithm
- optimal solution
- objective function