Parallel comparison of Illumina RNA-Seq and Affymetrix microarray platforms on transcriptomic profiles generated from 5-aza-deoxy-cytidine treated HT-29 colon cancer cells and simulated datasets.
Xiao XuYuanhao ZhangJennie WilliamsEric AntoniouW. Richard McCombieSong WuWei ZhuNicholas O. DavidsonPaula DenoyaEllen LiPublished in: BMC Bioinform. (2013)
Keyphrases
- microarray
- high throughput
- rna seq
- gene expression
- experimental conditions
- microarray datasets
- microarray data
- gene expression data
- gene expression profiles
- reference genome
- high dimensionality
- expression levels of thousands of genes
- gene ontology
- biological data
- gene selection
- molecular biology
- cancer classification
- microarray data analysis
- genomic data
- lung cancer
- early detection
- systems biology
- gene regulation
- protein protein interactions
- gene sets
- cancer diagnosis
- statistical analysis