A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements.
Alexander G. ChurbanovIgor VorechovskyChindo HicksPublished in: BMC Bioinform. (2010)
Keyphrases
- detection method
- high accuracy
- high precision
- data sets
- synthetic data
- experimental evaluation
- neural network
- preprocessing
- genetic algorithm
- dynamic programming
- pairwise
- context aware
- contextual information
- support vector machine svm
- objective function
- similarity measure
- segmentation method
- classification method
- network model