Virtual screening for compounds that mimic protein-protein interface epitopes.
Tim GeppertFelix ReisenMax PillongVolker HähnkeYusuf TanrikuluChristian P. KochAnna Maria PernaTatiana Batista PerezPetra SchneiderGisbert SchneiderPublished in: J. Comput. Chem. (2012)
Keyphrases
- virtual screening
- drug discovery
- protein protein
- binding sites
- high throughput
- systems biology
- protein protein interactions
- sequence data
- computational methods
- chemical compounds
- interaction networks
- gene expression
- dna sequences
- protein structure
- protein sequences
- early stage
- biological systems
- statistical significance
- biological networks
- discovery process