Accurate prediction of stability changes in protein mutants by combining machine learning with structure based computational mutagenesis.
Majid MassoIosif I. VaismanPublished in: Bioinform. (2008)
Keyphrases
- protein secondary structure prediction
- machine learning
- tertiary structure
- contact map
- protein secondary structure
- contact maps
- protein tertiary structure
- natural language processing
- subcellular localization
- learning algorithm
- prediction accuracy
- information extraction
- drug design
- neural network
- decision trees
- data analysis
- protein structure prediction
- learning tasks
- machine learning algorithms
- relational learning
- predicting protein
- computational biology
- knowledge representation
- computational methods
- prediction error
- physicochemical properties
- text classification