Stochastic modeling of aging cells reveals how damage accumulation, repair, and cell-division asymmetry affect clonal senescence and population fitness.
Ruijie SongMurat AcarPublished in: BMC Bioinform. (2019)
Keyphrases
- cell division
- confocal microscopy
- damage assessment
- population size
- mutation operator
- evolutionary algorithm
- fitness landscape
- immune memory
- microscopy images
- arabidopsis thaliana
- genetic algorithm
- cell cycle
- cell segmentation
- evolutionary strategy
- fitness function
- particle swarm optimization
- artificial immune
- differential evolution
- immune network
- multi objective
- convergence speed
- multiobjective optimization
- crossover operator
- immune response
- multi channel
- data sets
- automated detection
- data analysis