Masking residues using context-specific evolutionary conservation significantly improves short linear motif discovery.
Norman E. DaveyDenis C. ShieldsRichard J. EdwardsPublished in: Bioinform. (2009)
Keyphrases
- context specific
- motif discovery
- binding sites
- dna sequences
- biological sequences
- pattern discovery
- multiobjective optimization
- protein sequences
- data mining tasks
- domain specific
- evolutionary computation
- genetic algorithm
- computational biology
- objective function
- statistical significance
- multi objective
- amino acids
- gene expression
- min max
- general purpose
- transcription factors
- association rules
- sequence analysis
- data analysis