A hidden Markov approach for ascertaining cSNP genotypes from RNA sequence data in the presence of allelic imbalance by exploiting linkage disequilibrium.
Juan P. SteibelHeng WangPing-Shou ZhongPublished in: BMC Bioinform. (2015)
Keyphrases
- sequence data
- genome wide
- linkage disequilibrium
- nucleotide sequences
- high throughput
- sequence analysis
- genome sequences
- sequence classification
- association studies
- genetic variation
- human genome
- complex diseases
- genome wide association studies
- systems biology
- profile hidden markov models
- transcription factors
- data sources
- single nucleotide polymorphisms