Partial Order Optimum Likelihood (POOL): Maximum Likelihood Prediction of Protein Active Site Residues Using 3D Structure and Sequence Properties.
Wenxu TongYing WeiLeonel F. MurgaMary Jo OndrechenRonald J. WilliamsPublished in: PLoS Comput. Biol. (2009)
Keyphrases
- partial order
- tertiary structure
- maximum likelihood
- contact map
- amino acids
- protein tertiary structure
- amino acid residues
- physicochemical properties
- amino acid sequences
- secondary structure
- protein structure
- protein secondary structure prediction
- protein sequences
- multiple sequence alignments
- physico chemical
- protein structural
- total order
- partially ordered
- lattice structure
- protein structure prediction
- sequence similarity
- likelihood function
- solvent accessibility
- protein function
- sequence analysis
- protein folding
- predicting protein
- psi blast
- spatial structure
- protein structure alignment
- multiple sequence alignment
- experimentally determined
- conditional independencies
- sequence alignment
- sequential patterns
- prediction accuracy