Acceleration of the Pair-HMM forward algorithm on FPGA with cloud integration for GATK.
Rick WertenbroekYann ThomaPublished in: BIBM (2019)
Keyphrases
- improved algorithm
- preprocessing
- times faster
- segmentation algorithm
- computational complexity
- expectation maximization
- particle swarm optimization
- high speed
- dynamic programming
- detection algorithm
- hidden markov models
- computationally efficient
- high accuracy
- experimental evaluation
- cost function
- objective function
- parallel implementation
- matching algorithm
- hardware implementation
- learning algorithm
- worst case
- significant improvement
- k means
- evolutionary algorithm
- search space
- optimal solution