Computational Design of Potential Binder Protein for SARS-CoV-2 Spike RBD through A Novel Deep Neural Network Based-Protein Outpainting Algorithm.
Bingya DuanYingfei SunPublished in: BIBE (2021)
Keyphrases
- optimal solution
- detection algorithm
- learning algorithm
- cost function
- significant improvement
- np hard
- protein sequences
- convergence rate
- k means
- preprocessing
- search space
- dynamic programming
- experimental evaluation
- protein structure
- linear programming
- optimization algorithm
- computational complexity
- neural network
- molecular dynamics
- sequence alignment
- hardware implementation
- multiple sequence alignment
- worst case
- probabilistic model
- computational cost
- similarity measure
- genetic algorithm