Next generation sequencing reveals disparate population frequencies among cytochrome P450 genes: clinical pharmacogenomics of the CYP2 family.
William T. BuddGreg MeyersJeri R. DiltsKatherine O'HanlonJohn R. WoodyDavid G. BostwickJohn R. DruryThomas ReynoldsPublished in: Int. J. Comput. Biol. Drug Des. (2016)
Keyphrases
- single nucleotide polymorphisms
- genomic sequences
- rna seq
- dna microarray
- genome sequences
- gene expression
- high throughput
- dna sequences
- gene expression data
- human genome
- microarray data
- complex diseases
- genome wide
- clinical practice
- gene selection
- microarray gene expression data
- computational approaches
- special case
- microarray
- experimental conditions
- sequence data
- gene expression profiles
- gene regulatory networks
- clinical data
- medical data
- statistical methods
- microarray datasets
- biological processes
- cancer classification
- clinical trials
- chronic disease
- association studies