Drug Discovery Using Chemical Systems Biology: Repositioning the Safe Medicine Comtan to Treat Multi-Drug and Extensively Drug Resistant Tuberculosis.
Sarah L. KinningsNina LiuNancy BuchmeierPeter J. TongeLei XiePhilip E. BournePublished in: PLoS Comput. Biol. (2009)
Keyphrases
- drug discovery
- systems biology
- high throughput
- chemical compounds
- biological systems
- pharmaceutical industry
- virtual screening
- biological data
- biological networks
- gene regulatory networks
- molecular biology
- data mining
- protein protein interactions
- computational biology
- microarray
- early stage
- random walk
- natural language processing
- life sciences
- software engineering
- data model
- data analysis
- data sets