Transcription factor binding and nucleosome positioning are alternative pathways for transcription start site selection in eukaryotic promoters.
René DreosGiovanna AmbrosiniPhilipp BucherPublished in: IWBBIO (2014)
Keyphrases
- transcription factors
- cis regulatory
- transcription factor binding sites
- binding sites
- dna binding
- dna sequences
- transcriptional regulation
- microarray
- genome wide
- signaling pathways
- component analysis
- gene expression
- gene regulation
- chip seq
- systems biology
- computational biology
- biological processes
- regulatory networks
- co occurrence
- cell cycle
- sequence data
- high throughput
- saccharomyces cerevisiae
- highly correlated
- biomedical literature
- motif discovery
- data mining
- metabolic pathways
- machine learning
- data sets
- statistical significance