The La antigen inhibits the activation of the interferon-inducible protein kinase PKR by sequestering and unwinding double-stranded RNA.
Qiurong XiaoTyson V. SharpIan W. JeffreyMarion C. JamesGer J. M. PruijnWalther J. van VenrooijMichael J. ClemensPublished in: Nucleic Acids Res. (1994)
Keyphrases
- sequence alignment
- multiple alignment
- protein sequences
- nucleotide sequences
- secondary structure
- structural motifs
- amino acids
- rna secondary structures
- genome sequences
- biological data
- genome wide
- molecular biology
- protein structure
- pairwise
- sequence data
- sequence analysis
- genomic sequences
- high throughput
- protein folding
- information processing
- mass spectrometry
- dna sequences
- dynamic programming
- immune response
- amino acid sequences
- rna secondary structure prediction
- rna structures
- immune systems
- subcellular localization
- contact map
- dna binding
- protein function
- multiple sequence alignment
- protein structure prediction
- sequence similarity
- molecular dynamics
- artificial immune system
- rna sequences
- multiple sequence alignments
- computational biology
- genetic algorithm