Novel Method for Generating Structure-Based Pharmacophores Using Energetic Analysis.
Noeris K. SalamRoberto NutiWoody ShermanPublished in: J. Chem. Inf. Model. (2009)
Keyphrases
- evaluation method
- main contribution
- objective function
- theoretical analysis
- synthetic data
- optimization algorithm
- statistical analysis
- high accuracy
- dynamic programming
- cost function
- clustering method
- multiresolution
- tree structure
- medical images
- support vector machine
- experimental evaluation
- detection method
- segmentation method
- high precision
- fully automatic
- image analysis