On network-based kernel methods for protein-protein interactions with applications in protein functions prediction.
Limin LiWai-Ki ChingYatming ChanHiroshi MamitsukaPublished in: J. Syst. Sci. Complex. (2010)
Keyphrases
- kernel methods
- protein protein interactions
- protein function
- protein interaction
- predicting protein
- protein function prediction
- experimentally determined
- computational methods
- high throughput
- gene ontology
- biological processes
- protein protein
- support vector
- protein interaction networks
- network topology
- functional modules
- biological data
- support vector machine
- genomic data
- protein complexes
- network analysis
- feature space
- machine learning
- biomedical literature
- protein interaction data
- gene expression
- computational approaches
- protein sequences
- biological networks
- systems biology
- structural properties
- high precision
- interaction networks
- protein structure prediction
- computational tools
- secondary structure
- biological systems
- supervised learning
- pairwise
- similarity measure
- social networks