Optimizing genetic algorithm for protein crystallization screening using an exploratory fitness function.
Bidhan BhattaraiMidusha ShresthaRamazan S. AygünMarc L. PuseyPublished in: BIBM (2017)
Keyphrases
- fitness function
- genetic algorithm
- drug discovery
- genetic programming
- genetic algorithm ga
- evolutionary algorithm
- evolutionary computation
- genetic operators
- crossover and mutation
- crossover operator
- multi objective
- search space
- fitness evaluation
- protein structure
- particle swarm
- constrained optimization problems
- fuzzy logic
- evolutionary process
- initial population
- amino acids
- artificial neural networks
- evolutionary computing
- penalty function
- mutation operator
- protein sequences
- metaheuristic
- selection strategy
- particle swarm optimization pso
- optimization method
- evolutionary search
- real coded
- binary particle swarm optimization
- genetic algorithm is employed
- global search
- convergence speed
- hybrid algorithm
- candidate solutions
- differential evolution