Integrating regulatory DNA sequence and gene expression to predict genome-wide chromatin accessibility across cellular contexts.
Surag NairDaniel S. KimJacob PerriconeAnshul KundajePublished in: Bioinform. (2019)
Keyphrases
- transcription factors
- genome wide
- gene expression
- dna sequences
- high throughput
- dna binding
- gene regulation
- regulatory elements
- microarray
- regulatory networks
- binding sites
- human genome
- genomic data
- biological processes
- cell cycle
- differential expression
- transcriptional regulation
- motif discovery
- highly correlated
- signaling pathways
- microarray data
- gene sets
- transcription factor binding sites
- saccharomyces cerevisiae
- biological data
- gene expression profiles
- experimental conditions
- expression patterns
- high dimensionality
- high dimensional