Machine learning-assisted directed protein evolution with combinatorial libraries.
Zachary WuS. B. Jennifer KanRussell D. LewisBruce J. WittmannFrances H. ArnoldPublished in: Proc. Natl. Acad. Sci. USA (2019)
Keyphrases
- machine learning
- machine learning methods
- protein sequences
- data mining
- artificial intelligence
- learning algorithm
- computational biology
- machine learning algorithms
- text classification
- digital libraries
- knowledge acquisition
- computational intelligence
- data analysis
- predicting protein
- pattern recognition
- decision trees
- multimedia
- explanation based learning
- protein structure
- computer vision
- learning tasks
- protein classification
- computer science
- protein structure prediction
- mass spectrometry
- sequence alignment
- inductive logic programming
- statistical methods
- learning systems
- natural language processing
- information extraction
- inductive learning
- feature selection
- social networks
- reinforcement learning
- protein interaction networks
- protein protein interaction networks
- knowledge discovery
- molecular dynamics
- knowledge representation